The show takes a look at what it's like to live and work in space for months at a time. It feaures contributions from astronauts Rick Mastracchio, Koichi Wakata, Mike Hopkins and their families.
The show takes a look at the important work of the flight controllers, scientists, engineers and medics who help support the crew in space.
The viewers at home are given the chance to interact with the astronauts onboard the International Space Station 250 miles above Earth as they travel around the planet in 90 minutes. Dermot O'Leary and Mike Massimino are at Mission Control.