Accepting a wager from snooty Pi Nu president Harlan, Zipper unwisely bets his entire tuition that he can lure beautiful sorority girl Suzi Cooper into his bedroom by midnight. As the deadline approaches, Zipper's buddy Checko devises a plan to help his friend win the bet.
Checko, Ronald and Zipper find themselves saddled with the college president's tipsy daughter, and try to sneak her back to her room.
The angry sisters of Gamma Iota kidnap Zipper after suspecting him of stealing their diaries.
Scrambling to find Zipper a date for the Valentine's Day dance, the Pi Nu brothers settle on Seymour's overweight sister Marilyn, who is visiting for the weekend. As a prank, Harlan arranges for Zipper to be crowned "King of Hearts" at the dance.
After seeing his pals Checko and Ronald split up over a beautiful Asian student, Zipper tries to force a truce by locking them in the same room together - unaware that the fraternity house is on fire.
When Zipper's father arrives on campus for a visit, Checko and Ronald conspire to trick him into believing that his son is a model student. Since Harlan is out of town, Zipper attempts to pose as president of the fraternity.
Checko and Ronald attempt to cure Zipper of his tendency to hiccup when excited, which has been sabotaging his romantic life. Meanwhile, Harlan finds out and tells everyone.
Checko, Ronald and Zipper organize their own version of "The Newlywed Game" after enrolling in a marriage survival course that requires pairing off with a female partner.
En route to Florida for spring break, Checko, Ronald and Zipper end up stranded at a seedy roadside diner when their car breaks down. They are shocked to discover the snobbish Mary Lee working as a waitress.
Zipper creates chaos when he rescues a chimpanzee from a fatal research experiment. Mary Lee is none too happy when she winds up baby-sitting the lovable chimp, who mimics her every move.
Harlan challenges Ronald to a boxing match to defend Mary Lee's honor, while Checko and Zipper take bets.
When Harlan cheats on a calculus exam and Zipper is mistakenly accused, Zipper has to decide whether to accept a failing grade or tell on Harlan.