Doyle and Aimee arrive at Galaxy High and meet their strange new classmates. Here, their roles are switched, as Doyle is now a nerd and Aimee is popular.
Doyle must make a pizza delivery to the creep Tinglar planet. But Beef and the Bonk Bunch Follow Him to Make Trouble.
Beef is elected king of the planet Cholesterol. But once he gets crowned. they want to eat him and Doyle must save him.
Milo disappears after he angers his friends by making a couple of accidents.
Booey wants to go to the Mick Maggers concert, but the tickets are sold out. Aimee and the gang go to great lengths to get a ticket for Booey.
The Hands Across the Universe dance is coming to Galaxy High, and Doyle's new friend Wolfgang arrives to help with the dance and play practical jokes on everyone.
Aimee is persued by Reggie Unicycle, the richest man in the galaxy. He showers her with gifts and trips, and the gang must help her see him for what he really is.
Everyone, but Doyle gets to go for Spring Break at Fort Lauderoid. But Doyle and Professor Icenstein find out that a supernova nearby will destroy the beach plantoid.
To get better grades, Doyle tries a brain blaster and gets addicted. He steals from his friends in order to pay for his habit, but Aimee and friends try to break him off of the drug.
Beef is punished by Ms. McBrain to take over a class full of little kids. who are alot of trouble.
Doyle, Aimee, Milo and Creep fall into Professor Icenstein's time machine and go back to the day that Galaxy High was founded. But by being there,they alter time and have to make sure that Galaxy High gets created somehow.
Everyone but Doyle, Aimee and Professor Icenstein get the Martian Mumps,a disease that turns everyone green and dull. They must find a cure soon or the students and teachers will remain martians forever.
At a big game, Doyle is knocked out, and wakes up 15 years later to find he has grown into a giant. All the former Galaxy High students are on Earth and Beef's army has been ordered to destroy Doyle.